Pub. Date : 2019 Jul
PMID : 30776417
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms. | Vancomycin | major histocompatibility complex, class I, A | Homo sapiens |
| 2 | Time-to-event analysis of DRESS development during vancomycin treatment among the HLA-A*32:01-positive group indicated that 19.2% had DRESS and did so within 4 weeks. | Vancomycin | major histocompatibility complex, class I, A | Homo sapiens |
| 3 | CONCLUSIONS: HLA-A*32:01 is strongly associated with vancomycin-induced DRESS in a population of predominantly European ancestry. | Vancomycin | major histocompatibility complex, class I, A | Homo sapiens |
| 4 | HLA-A*32:01 testing could improve antibiotic safety, help implicate vancomycin as the causal drug, and preserve future treatment options with coadministered antibiotics. | Vancomycin | major histocompatibility complex, class I, A | Homo sapiens |