Title : Celastrol suppresses nitric oxide synthases and the angiogenesis pathway in colorectal cancer.

Pub. Date : 2019 Mar

PMID : 30773944






1 Functional Relationships(s)
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1 Treatment with celastrol inhibited colorectal cancer cell growth and migration, and was associated with suppression of the expression of key genes (TYMP, CDH5, THBS2, LEP, MMP9, and TNF) and proteins (IL-1b, MMP-9, PDGF, Serpin E1, and TIMP-4) involved in the angiogenesis pathway. celastrol tumor necrosis factor Homo sapiens