Pub. Date : 2019 Jun 15
PMID : 30768980
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | alpha1D-adrenoceptor involves the relaxation effect of farrerol in rat aortic vascular smooth muscle cells. | farrerol | adrenoceptor alpha 1D | Rattus norvegicus |
| 2 | When the cells were transfected with lentivirus mediated alpha1D-adrenoceptor gene-shRNA, the effects of farrerol on changes induced by AngII in rat aortic VSMCs were markedly reversed. | farrerol | adrenoceptor alpha 1D | Rattus norvegicus |
| 3 | In conclusion, farrerol could produce relaxtion effect in rat aortic VSMCs precontracted by 10 muMu AngII, which was involved in downregulation expression of MLCK and SM22alpha, and inhibition phosphorylation level of MYPT1 and MLC via activating alpha1D-adrenoceptor gene. | farrerol | adrenoceptor alpha 1D | Rattus norvegicus |