Title : PCB 126 induces monocyte/macrophage polarization and inflammation through AhR and NF-κB pathways.

Pub. Date : 2019 Mar 15

PMID : 30768972






2 Functional Relationships(s)
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1 Since dioxin-like PCBs may elicit inflammatory cascades through multiple mechanisms, we then pretreated macrophages with both aryl hydrocarbon receptor (AhR) and NF-kappaB antagonists prior to PCB treatment. Dioxins pyruvate carboxylase Homo sapiens
2 Our data demonstrate the involvement of PCB 126 in macrophage polarization and inflammation, indicating another important role of dioxin-like PCBs in the pathology of atherosclerosis. Dioxins pyruvate carboxylase Homo sapiens