Title : Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis.

Pub. Date : 2019 Sep

PMID : 30765471






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In ABCB7-depleted cells, defective heme biosynthesis resulted from translational repression of ALAS2 by iron regulatory proteins and from decreased stability of the terminal enzyme ferrochelatase. Heme 5'-aminolevulinate synthase 2 Homo sapiens