Title : Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative.

Pub. Date : 1988

PMID : 3076125






4 Functional Relationships(s)
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1 Lovastatin (MK-803, mevinolin) and simvastatin (MK-733, synvinolin), 2 highly potent 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors, have been heralded as breakthrough therapy for the treatment of atherosclerotic disease. Simvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
2 Lovastatin (MK-803, mevinolin) and simvastatin (MK-733, synvinolin), 2 highly potent 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors, have been heralded as breakthrough therapy for the treatment of atherosclerotic disease. Simvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
3 Lovastatin (MK-803, mevinolin) and simvastatin (MK-733, synvinolin), 2 highly potent 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors, have been heralded as breakthrough therapy for the treatment of atherosclerotic disease. Simvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
4 Lovastatin and simvastatin are the first HMG CoA reductase inhibitors to receive regulatory agency approval for marketed use. Simvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens