Title : Exemestane may be less detrimental than letrozole to bone health in women homozygous for the UGT2B17*2 gene deletion.

Pub. Date : 2019 Jun

PMID : 30747308






1 Functional Relationships(s)
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1 UGT2B17 genotype was not associated with changes in BMD from 24 months of AI treatment, though in UGT2B17*2 homozygous patients, there was a trend toward greater decreases in BMD of the spine from treatment with letrozole compared with exemestane (P = 0.05). Letrozole UDP glucuronosyltransferase family 2 member B17 Homo sapiens