Pub. Date : 2019 Apr
PMID : 30737648
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | GD induced cell death, which was augmented by eEF2K gene knockdown using a small interfering RNA. | Gadolinium | eukaryotic elongation factor-2 kinase | Rattus norvegicus |
2 | In contrast, eEF2K gene knockdown significantly inhibited GD-induced increase of LC3-II to LC3-I ratio and autophagosome formation as determined by an immunofluorescence staining. | Gadolinium | eukaryotic elongation factor-2 kinase | Rattus norvegicus |
3 | Further, eEF2K gene knockdown significantly inhibited GD-induced phosphorylation of adenosine monophosphate-activated protein kinase (AMPK)alpha and its downstream substrate, unc-51 like autophagy activating kinase (ULK)1. | Gadolinium | eukaryotic elongation factor-2 kinase | Rattus norvegicus |