Pub. Date : 2019 Apr 1
PMID : 30735434
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The transient receptor potential ankyrin 1 (TRPA1) mediates pain signaling and is activated by unsaturated aldehydes, including acrolein and 4-hydroxynonenal. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |
| 2 | The transient receptor potential ankyrin 1 (TRPA1) mediates pain signaling and is activated by unsaturated aldehydes, including acrolein and 4-hydroxynonenal. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |
| 3 | A role of TRPA1 in cardiomyocyte toxicity was demonstrated in isolated cardiomyocytes exposed to acrolein, an I/R-associated toxin that induces Ca2+ accumulation and hypercontraction, effects significantly blunted by HC-030031, a TRPA1 antagonist. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |
| 4 | A role of TRPA1 in cardiomyocyte toxicity was demonstrated in isolated cardiomyocytes exposed to acrolein, an I/R-associated toxin that induces Ca2+ accumulation and hypercontraction, effects significantly blunted by HC-030031, a TRPA1 antagonist. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |
| 5 | Functional TRPA1 in cardiomyocytes was enriched in intercalated disks and contributed to acrolein-induced Ca2+ overload and hypercontraction. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |