Title : The TRPV4 Agonist GSK1016790A Regulates the Membrane Expression of TRPV4 Channels.

Pub. Date : 2019

PMID : 30728775






1 Functional Relationships(s)
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1 Further, we show that the density of TRPV4 at the plasma membrane decreased within 20 min, as they translocate to the recycling endosomes and that the surface density is dependent on the release of calcium from the intracellular stores and is controlled via a PI3K, PKC, and RhoA signaling pathway. Calcium transient receptor potential cation channel subfamily V member 4 Homo sapiens