Title : Design, Synthesis, Pharmacological Evaluation and Vascular Effects of Delphinidin Analogues.

Pub. Date : 2018

PMID : 30727871






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 It has also been highlighted that Dp interacts directly with the active site of estrogen receptor alpha (ERalpha), leading to activation of endothelial NO synthase (eNOS) pathway thus contributing to the prevention of endothelial dysfunction in mice aorta. delphinidin estrogen receptor 1 (alpha) Mus musculus
2 It has also been highlighted that Dp interacts directly with the active site of estrogen receptor alpha (ERalpha), leading to activation of endothelial NO synthase (eNOS) pathway thus contributing to the prevention of endothelial dysfunction in mice aorta. delphinidin estrogen receptor 1 (alpha) Mus musculus
3 OBJECTIVE: The aim of this study was to identify new Dp analogues with increased lipophilicity and vasorelaxation potential by a chemical modulation of its structure and to characterize the signaling pathway notably in relation with ERalpha signaling and nitric oxide (NO) production. delphinidin estrogen receptor 1 (alpha) Mus musculus