Title : A novel mechanism for the anticancer activity of aspirin and salicylates.

Pub. Date : 2019 Apr

PMID : 30720135






4 Functional Relationships(s)
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1 Taken together and in light of our previous findings that the aspirin-like analogues can affect cyclin D1 expression and nuclear factor-kappaB localisation, it was hypothesized that aspirin and aspirin analogues significantly and swiftly perturb the EGFR axis and that the protective activity of aspirin may in part be explained by perturbed EGFR internalisation and activation. Aspirin cyclin D1 Homo sapiens
2 Taken together and in light of our previous findings that the aspirin-like analogues can affect cyclin D1 expression and nuclear factor-kappaB localisation, it was hypothesized that aspirin and aspirin analogues significantly and swiftly perturb the EGFR axis and that the protective activity of aspirin may in part be explained by perturbed EGFR internalisation and activation. Aspirin cyclin D1 Homo sapiens
3 Taken together and in light of our previous findings that the aspirin-like analogues can affect cyclin D1 expression and nuclear factor-kappaB localisation, it was hypothesized that aspirin and aspirin analogues significantly and swiftly perturb the EGFR axis and that the protective activity of aspirin may in part be explained by perturbed EGFR internalisation and activation. Aspirin cyclin D1 Homo sapiens
4 Taken together and in light of our previous findings that the aspirin-like analogues can affect cyclin D1 expression and nuclear factor-kappaB localisation, it was hypothesized that aspirin and aspirin analogues significantly and swiftly perturb the EGFR axis and that the protective activity of aspirin may in part be explained by perturbed EGFR internalisation and activation. Aspirin cyclin D1 Homo sapiens