Title : Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures.

Pub. Date : 2019 Jan 28

PMID : 30692572






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 (S)-crizotinib reduced tyrosine phosphorylation of c-MET and ErbB3 whereas TH588 induced a mitotic cell cycle arrest, which was not affected by adding ROS-modulating compounds. Tyrosine MET proto-oncogene, receptor tyrosine kinase Homo sapiens