Pub. Date : 2019 May
PMID : 30690843
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In terms of mechanism, we pretreated fibroblasts with the endoplasmic reticulum stress (ER) inhibitor salubrinal and RNA-dependent protein kinase-like ER kinase (PERK) short hairpin RNA, these treatments abolished the inhibitory effects of HCPT on fibrosis, thereby suggesting that HCPT"s inhibition of TGF-beta1-induced tendon fibrosis might be mediated by the PERK signaling pathway in vitro. | hydroxycamptothecinum | transforming growth factor beta 1 | Homo sapiens |