Pub. Date : 2019 Apr 5
PMID : 30689993
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For example, activation of serotonin 5-HT2C GPCRs is pharmacotherapeutic for obesity, but there is tolerance to the anorectic effect of the only approved 5-HT2C agonist, lorcaserin. | lorcaserin | 5-hydroxytryptamine receptor 2C | Homo sapiens |
| 2 | For example, activation of serotonin 5-HT2C GPCRs is pharmacotherapeutic for obesity, but there is tolerance to the anorectic effect of the only approved 5-HT2C agonist, lorcaserin. | lorcaserin | 5-hydroxytryptamine receptor 2C | Homo sapiens |
| 3 | Lorcaserin, which displays potency and efficacy equal to 5-HT, desensitized the 5-HT2C receptor significantly more than 5-HT (p<0.05). | lorcaserin | 5-hydroxytryptamine receptor 2C | Homo sapiens |