Title : YB-1 modulates the drug resistance of glioma cells by activation of MDM2/p53 pathway.

Pub. Date : 2019

PMID : 30679904






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Overexpression of YB-1 or MDM2 renders a drug resistance feature in glioma cell exposed to temozolomide (TMZ), by directly targeting p53. Temozolomide transformed mouse 3T3 cell double minute 2 Mus musculus
2 Overexpression of YB-1 or MDM2 renders a drug resistance feature in glioma cell exposed to temozolomide (TMZ), by directly targeting p53. Temozolomide transformed mouse 3T3 cell double minute 2 Mus musculus
3 Genetic or chemical inhibition of MDM2 significantly blocked YB-1-modulated response of glioma cells to TMZ. Temozolomide transformed mouse 3T3 cell double minute 2 Mus musculus