Title : 5-Fluorouracil Induces Enteric Neuron Death and Glial Activation During Intestinal Mucositis via a S100B-RAGE-NFκB-Dependent Pathway.

Pub. Date : 2019 Jan 24

PMID : 30679569






1 Functional Relationships(s)
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1 Furthermore, 5-FU increased RAGE and NFkappaB NLS immunostaining in enteric neurons, associated with a significant increase in the nitrite/nitrate, IL-6 and TNF-alpha levels, iNOS expression and MDA accumulation in the small intestine. Fluorouracil tumor necrosis factor Homo sapiens