Pub. Date : 2019 Apr
PMID : 30677511
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Involvement of estrogen receptor and GPER in bisphenol A induced proliferation of vascular smooth muscle cells. | bisphenol A | estrogen receptor 1 | Homo sapiens |
2 | Blocking the functions of ERalpha and GPER by their specific inhibitors can attenuate the BPA induced proliferation of VSMCs and expression of Ang II. | bisphenol A | estrogen receptor 1 | Homo sapiens |
3 | Consistently, BPA induced expression of TNFalpha and IL-6 was also attenuated by inhibitors of ERalpha and GPER. | bisphenol A | estrogen receptor 1 | Homo sapiens |
4 | Collectively, our present study suggested that BPA can trigger the proliferation of VSMCs via both ERalpha and GPER dependent manners. | bisphenol A | estrogen receptor 1 | Homo sapiens |