Title : Involvement of estrogen receptor and GPER in bisphenol A induced proliferation of vascular smooth muscle cells.

Pub. Date : 2019 Apr

PMID : 30677511






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Involvement of estrogen receptor and GPER in bisphenol A induced proliferation of vascular smooth muscle cells. bisphenol A estrogen receptor 1 Homo sapiens
2 Blocking the functions of ERalpha and GPER by their specific inhibitors can attenuate the BPA induced proliferation of VSMCs and expression of Ang II. bisphenol A estrogen receptor 1 Homo sapiens
3 Consistently, BPA induced expression of TNFalpha and IL-6 was also attenuated by inhibitors of ERalpha and GPER. bisphenol A estrogen receptor 1 Homo sapiens
4 Collectively, our present study suggested that BPA can trigger the proliferation of VSMCs via both ERalpha and GPER dependent manners. bisphenol A estrogen receptor 1 Homo sapiens