Title : An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade.

Pub. Date : 2019 Apr 1

PMID : 30674531






1 Functional Relationships(s)
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1 Moreover, GB1107 potentiated the effects of a PD-L1 immune checkpoint inhibitor to increase expression of cytotoxic (IFNgamma, granzyme B, perforin-1, Fas ligand) and apoptotic (cleaved caspase-3) effector molecules. GB1107 perforin 1 (pore forming protein) Mus musculus