Title : The central role of inflammatory signaling in the pathogenesis of myelodysplastic syndromes.

Pub. Date : 2019 Mar 7

PMID : 30670444






1 Functional Relationships(s)
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1 Furthermore, somatic gene mutations of varied functional classes license the NLRP3 inflammasome to generate a common phenotype with excess reactive oxygen species generation, Wnt/beta-catenin-induced proliferation, cation flux-induced cell swelling, and caspase-1 activation. oxygen species NLR family pyrin domain containing 3 Homo sapiens