Title : Diagnostic Accuracy of Monocyte Chemotactic Protein (MCP)-2 as Biomarker in Response to PE35/PPE68 Proteins: A Promising Diagnostic Method for the Discrimination of Active and Latent Tuberculosis.

Pub. Date : 2019

PMID : 30663558






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The aim of the current study was to evaluate the potential of in vitro antigenspecific expression of Monocyte Chemotactic Protein (MCP)-2 for discrimination of ATB and LTBI after stimulation of whole blood with PE35 and PPE68 recombinant proteins. atb C-C motif chemokine ligand 8 Homo sapiens
2 RESULTS: The median MCP-2 response to both PE35 and PPE68 in those with LTBI was significantly higher than patients with ATB. atb C-C motif chemokine ligand 8 Homo sapiens
3 The discrimination performance of MCP-2 response following stimulation of PE35 (assessed by AUC) between LTBI and patients with ATB was 0.98 (95%CI: 0.94-1.00). atb C-C motif chemokine ligand 8 Homo sapiens
4 CONCLUSION: MCP-2 induced by PE35 and PPE68 shows good discriminatory power for discrimination of ATB and LTBI. atb C-C motif chemokine ligand 8 Homo sapiens