Title : Single-channel permeability and glycerol affinity of human aquaglyceroporin AQP3.

Pub. Date : 2019 Apr 1

PMID : 30659792






3 Functional Relationships(s)
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1 This research is focused on two of the remaining questions: How permeable is AQP3 to water? Water aquaporin 3 (Gill blood group) Homo sapiens
2 Through atomistic modelling and large-scale simulations, we found that AQP3 is two to three times more permeable to water than AQP1 and that the glycerol-AQP3 affinity is approximately 500/M. Water aquaporin 3 (Gill blood group) Homo sapiens
3 We observed close agreement between the experimentally measured and the computationally predicted time courses of erythrocytes, which corroborated our computational conclusions on the AQP3 water-permeability and the glycerol-AQP3 affinity. Water aquaporin 3 (Gill blood group) Homo sapiens