Title : Genistein inhibits stemness of SKOV3 cells induced by macrophages co-cultured with ovarian cancer stem-like cells through IL-8/STAT3 axis.

Pub. Date : 2019 Jan 15

PMID : 30646963






2 Functional Relationships(s)
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Protein Name
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1 Genistein inhibits stemness of SKOV3 cells induced by macrophages co-cultured with ovarian cancer stem-like cells through IL-8/STAT3 axis. Genistein C-X-C motif chemokine ligand 8 Homo sapiens
2 Moreover, depletion or addition of IL-8 enhanced or attenuated the effect of GEN. Additionally, knockdown or overepression of STAT3 in THP-1 macrophages potentiated or attenuated the inhibitory effects of GEN. Genistein C-X-C motif chemokine ligand 8 Homo sapiens