Title : Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation.

Pub. Date : 2018

PMID : 30622668

1 Functional Relationships(s)
Compound Name
Protein Name
1 Kallistatin via its heparin-binding site antagonizes TNF-alpha-induced senescence and superoxide formation, while kallistatin"s active site is essential for inhibiting miR-34a synthesis, thus elevating sirtuin 1 (SIRT1)/eNOS synthesis in EPCs. Superoxides tumor necrosis factor Homo sapiens