Title : The human innate immune protein calprotectin induces iron starvation responses in Pseudomonas aeruginosa.

Pub. Date : 2019 Mar 8

PMID : 30622135






2 Functional Relationships(s)
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1 Here, we report that human calprotectin (CP; S100A8/S100A9 or MRP8/MRP14 heterooligomer) inhibits iron uptake and induces an iron starvation response in Pseudomonas aeruginosa cells by sequestering Fe(II) at its unusual His6 site. Iron S100 calcium binding protein A9 Homo sapiens
2 Here, we report that human calprotectin (CP; S100A8/S100A9 or MRP8/MRP14 heterooligomer) inhibits iron uptake and induces an iron starvation response in Pseudomonas aeruginosa cells by sequestering Fe(II) at its unusual His6 site. Iron S100 calcium binding protein A9 Homo sapiens