Title : Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma.

Pub. Date : 2019 Jan 8

PMID : 30621754






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1 Moreover, autophagy induced by XAG was mediated by activating endoplasmic reticulum stress (ERS), along with administration of XAG, the expression levels of ERS-associated proteins, including CHOP, GRP78, ATF6, p-eIF2alpha, IRE1alpha, and cleaved caspase-12 were significantly increased in HCC cells. xanthoangelol heat shock protein family A (Hsp70) member 5 Homo sapiens