Pub. Date : 2019 Jan 2
PMID : 30609754
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer. | Glucose | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Macropinocytosis is increased in these glucose independent cells, and is regulated by phosphoinositide 3-kinase (PI3K) activation of Rac-Pak signaling. | Glucose | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Furthermore, inhibition of Rac-dependent macropinocytosis blocks glucose-independent proliferation. | Glucose | AKT serine/threonine kinase 1 | Homo sapiens |