Title : Melatonin ameliorates intervertebral disc degeneration via the potential mechanisms of mitophagy induction and apoptosis inhibition.

Pub. Date : 2019 Mar

PMID : 30609271






1 Functional Relationships(s)
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1 In addition, melatonin was demonstrated to preserve the extracellular matrix (ECM) content of Collagen II, Aggrecan and Sox-9, while inhibiting the expression of matrix degeneration enzymes, including MMP-13 and ADAMTS-5. Melatonin ADAM metallopeptidase with thrombospondin type 1 motif 5 Homo sapiens