Title : Direct stimulation of adenylyl cyclase 9 by the fungicide imidazole miconazole.

Pub. Date : 2019 Apr

PMID : 30607468






1 Functional Relationships(s)
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1 In crude membranes, the activity of AC9 in the presence of GDP-beta-S was enhanced by miconazole with an EC50 of ~ 8 muM, while AC1 and AC2 were inhibited with an IC50 of ~ 20 muM. guanosine 5'-O-(2-thiodiphosphate) adenylate cyclase 9 Homo sapiens