Title : Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington's Disease.

Pub. Date : 2019

PMID : 30594931






1 Functional Relationships(s)
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1 BACKGROUND: Previous studies suggest that Huntingtin, the protein mutated in Huntington"s disease (HD), is required for actin based changes in cell morphology, and undergoes stimulus induced targeting to plasma membranes where it interacts with phospholipids involved in cell signaling. Phospholipids huntingtin Homo sapiens