Title : Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP-2 pathway.

Pub. Date : 2019 Apr

PMID : 30592645






1 Functional Relationships(s)
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1 Here, we asked whether the activity of the sterol regulatory element-binding protein 2 (SREBP-2) pathway, which regulates the cholesterol content in membranes, affects the susceptibility of target cells toward toxins A and B. Sterols sterol regulatory element binding transcription factor 2 Rattus norvegicus