Pub. Date : 2019 Feb
PMID : 30575269
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We demonstrated that MPK-1 contributes to RSV-mediated longevity through nuclear accumulation of SKN-1 in a SIR-2.1/DAF-16 pathway-independent manner. | Resveratrol | BZIP domain-containing protein;Protein skinhead-1 | Caenorhabditis elegans |
| 2 | The positive effect of RSV in regulating lifespan was completely abolished by RNA interference against mpk-1 in the sir-2.1 and daf-16 mutants, strongly indicating that the MPK-1/SKN-1 pathway is involved in RSV-mediated longevity, independently of SIR-2.1/DAF-16. | Resveratrol | BZIP domain-containing protein;Protein skinhead-1 | Caenorhabditis elegans |
| 3 | The positive effect of RSV in regulating lifespan was completely abolished by RNA interference against mpk-1 in the sir-2.1 and daf-16 mutants, strongly indicating that the MPK-1/SKN-1 pathway is involved in RSV-mediated longevity, independently of SIR-2.1/DAF-16. | Resveratrol | BZIP domain-containing protein;Protein skinhead-1 | Caenorhabditis elegans |