Title : Genetic Association and Altered Gene Expression of CYBB in Multiple Sclerosis Patients.

Pub. Date : 2018 Dec 18

PMID : 30567305






1 Functional Relationships(s)
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1 In this work, we screened for association with MS 11 single nucleotide polymorphisms (SNPs) and two microsatellite markers in the five genes (NCF1, NCF2, NCF4, CYBA, and CYBB) of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX2) system, the enzymatic pathway producing ROS in the brain and neural tissues, in 347 Finnish patients with MS and 714 unaffected family members. NAD cytochrome b-245 beta chain Homo sapiens