Title : The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release.

Pub. Date : 2018

PMID : 30564747






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Dihydrofolate reductase (DHFR) catalyzes the stereospecific reduction of 7,8-dihydrofolate (FH2) to (6s)-5,6,7,8-tetrahydrofolate (FH4) via hydride transfer from NADPH. dihydrofolate Dihydrofolate reductase Escherichia coli
2 Dihydrofolate reductase (DHFR) catalyzes the stereospecific reduction of 7,8-dihydrofolate (FH2) to (6s)-5,6,7,8-tetrahydrofolate (FH4) via hydride transfer from NADPH. dihydrofolate Dihydrofolate reductase Escherichia coli