Title : Anti-Invasive and Anti-Proliferative Effects of shRNA-Loaded Poly(Lactide-Co-Glycolide) Nanoparticles Following RAN Silencing in MDA-MB231 Breast Cancer Cells.

Pub. Date : 2018 Dec 17

PMID : 30560466






1 Functional Relationships(s)
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1 BACKGROUND: Overexpression of the RAN GTP (RAN) gene has been shown to be linked to metastatic activity of MDA-MB231 human breast cancer cells by increasing Ras/MEK/ERK and PI3K/Akt/mTORC1 signalling. Guanosine Triphosphate AKT serine/threonine kinase 1 Homo sapiens