Pub. Date : 2018
PMID : 30555244
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Vandetanib (ZD6474) induces antiangiogenesis through mTOR-HIF-1 alpha-VEGF signaling axis in breast cancer cells. | vandetanib | vascular endothelial growth factor A | Homo sapiens |
| 2 | Vandetanib (ZD6474) induces antiangiogenesis through mTOR-HIF-1 alpha-VEGF signaling axis in breast cancer cells. | vandetanib | vascular endothelial growth factor A | Homo sapiens |
| 3 | Vandetanib can reduce both mRNA and protein level of mTOR, HIF-1 alpha, and VEGF. | vandetanib | vascular endothelial growth factor A | Homo sapiens |
| 4 | Conclusion: In short, our study showed that vandetanib can control angiogenesis of breast cancer in culture via mTOR, HIF-1 alpha, and VEGF signaling pathway. | vandetanib | vascular endothelial growth factor A | Homo sapiens |