Title : Betulinic acid inhibits the migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis.

Pub. Date : 2019 Feb

PMID : 30553912






2 Functional Relationships(s)
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1 In addition, we found that the mRNA expression of IL-1beta, IL-6, IL-8 and IL-17A were markedly down-regulated by treatment with betulinic acid in TNF-alpha-induced RA FLSs. betulinic acid tumor necrosis factor Homo sapiens
2 The results indicated that betulinic acid treatment reduced the TNF-alpha-induced activation of NF-kappaB signal pathway and the NF-kappaB nuclear accumulation. betulinic acid tumor necrosis factor Homo sapiens