Pub. Date : 2018
PMID : 30538568
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | For cases with comparably low DPD activity, advisable primary and subsequent dose adjustment of 5-fluorouracil based on plasma 5-fluorouracil levels may be a practical strategy for reducing the occurrence of adverse reactions for personalized treatment of the UGT1A1*6 or UGT1A1*28 heterozygous type. | Fluorouracil | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
2 | For cases with comparably low DPD activity, advisable primary and subsequent dose adjustment of 5-fluorouracil based on plasma 5-fluorouracil levels may be a practical strategy for reducing the occurrence of adverse reactions for personalized treatment of the UGT1A1*6 or UGT1A1*28 heterozygous type. | Fluorouracil | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
3 | For cases with comparably low DPD activity, advisable primary and subsequent dose adjustment of 5-fluorouracil based on plasma 5-fluorouracil levels may be a practical strategy for reducing the occurrence of adverse reactions for personalized treatment of the UGT1A1*6 or UGT1A1*28 heterozygous type. | Fluorouracil | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
4 | For cases with comparably low DPD activity, advisable primary and subsequent dose adjustment of 5-fluorouracil based on plasma 5-fluorouracil levels may be a practical strategy for reducing the occurrence of adverse reactions for personalized treatment of the UGT1A1*6 or UGT1A1*28 heterozygous type. | Fluorouracil | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |