Title : Effect of lentivirus-mediated overexpression or silencing of MnSOD on apoptosis of resveratrol-treated fibroblast-like synoviocytes in rheumatoid arthritis.

Pub. Date : 2019 Feb 5

PMID : 30529106






1 Functional Relationships(s)
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1 Compared with the NC group, the MnSOD overexpression group treated with different concentrations of Res (0, 25, 50, 100, or 200 muM) and 5 muM H2O2 showed reduced levels of mitochondrial reactive oxygen species, increased B-cell-lymphoma-2 (Bcl-2), reduced Bcl-2 Associated X protein (Bax), and fewer apoptotic cells. Hydrogen Peroxide superoxide dismutase 2 Rattus norvegicus