Title : Oxidative and inflammatory mediators are upregulated in neutrophils of autistic children: Role of IL-17A receptor signaling.

Pub. Date : 2019 Mar 2

PMID : 30529000






1 Functional Relationships(s)
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1 Furthermore, activation of IL-17A/IL-17R signaling in neutrophils of ASD subjects leads to upregulation of phospho-NFkappaB, IL-6 and NOX2/ROS, thus suggesting a compelling role of IL-17A in modulation of inflammation. Reactive Oxygen Species interleukin 17A Homo sapiens