Pub. Date : 2018
PMID : 30524241
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that isoflurane GA caused upregulations of hippocampal NLRP3, cleaved caspase-1, interleukin-1beta (IL-1beta), and IL-18 and the activation of pyroptosis, which is NLRP3 inflammasome-dependent; this consequently gave rise to neuronal damage and cognitive impairment in aged mice. | Isoflurane | interleukin 1 beta | Mus musculus |
| 2 | We found that isoflurane GA caused upregulations of hippocampal NLRP3, cleaved caspase-1, interleukin-1beta (IL-1beta), and IL-18 and the activation of pyroptosis, which is NLRP3 inflammasome-dependent; this consequently gave rise to neuronal damage and cognitive impairment in aged mice. | Isoflurane | interleukin 1 beta | Mus musculus |