Title : TGF-β downregulation-induced cancer cell death is finely regulated by the SAPK signaling cascade.

Pub. Date : 2018 Dec 6

PMID : 30523245






3 Functional Relationships(s)
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1 The expression levels of Trx and GSTM1, which encode inhibitory proteins that bind to ASK1, were reduced, likely a result of the altered translocation of Smad complex proteins rather than from ROS production. Reactive Oxygen Species thioredoxin Homo sapiens
2 Instead, both ROS and ROS-mediated ER stress were responsible for the decrease in interactions between ASK1 and Trx or GSTM1. Reactive Oxygen Species thioredoxin Homo sapiens
3 Instead, both ROS and ROS-mediated ER stress were responsible for the decrease in interactions between ASK1 and Trx or GSTM1. Reactive Oxygen Species thioredoxin Homo sapiens