Title : Gankyrin drives metabolic reprogramming to promote tumorigenesis, metastasis and drug resistance through activating β-catenin/c-Myc signaling in human hepatocellular carcinoma.

Pub. Date : 2019 Feb 28

PMID : 30503555






1 Functional Relationships(s)
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1 c-Myc inhibitor synergizes with Sorafenib or Regorafenib to suppress HCC PDX tumors with high Gankyrin levels. Sorafenib MYC proto-oncogene, bHLH transcription factor Homo sapiens