Pub. Date : 2019 Jan
PMID : 30502252
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The rats were intraperitoneally injected with either the vehicle or a selective SIRT3 inhibitor (3-TYP) and scarified at different time points (4, 8, and 24 h after I/R). | 3-TYP | sirtuin 3 | Rattus norvegicus |
2 | Moreover, SIRT3 suppression by 3-TYP treatment (comparing with the vehicle treatment group) aggravated AKI, as evidenced by increased indicators of oxidative stress (increased mitochondrial red fluorescence MitoSOX and decreased reduced glutathione/oxidized glutathione ratio, all P values < 0.01). | 3-TYP | sirtuin 3 | Rattus norvegicus |