Pub. Date : 2018
PMID : 30497079
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Here we report that treating ETR cells with Tam or Fulvestrant increases H19 expression and that it"s decreased expression overcomes resistance to Tam and Fulvestrant in these cells. | Tamoxifen | H19 imprinted maternally expressed transcript | Homo sapiens |
| 2 | Interestingly, H19 expression is regulated by Notch and HGF signaling in the ETR cells and pharmacological inhibitors of Notch and c-MET signaling together significantly reverse resistance to Tam and Fulvestrant in an H19-dependent manner in these cells. | Tamoxifen | H19 imprinted maternally expressed transcript | Homo sapiens |