Title : Use of Levosimendan in Intensive Care Unit Settings: An Opinion Paper.

Pub. Date : 2019 Jan

PMID : 30489437






1 Functional Relationships(s)
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1 Levosimendan is an inodilator that promotes cardiac contractility primarily through calcium sensitization of cardiac troponin C and vasodilatation via opening of adenosine triphosphate-sensitive potassium (KATP) channels in vascular smooth muscle cells; the drug also exerts organ-protective effects through a similar effect on mitochondrial KATP channels. Simendan troponin C1, slow skeletal and cardiac type Homo sapiens