Pub. Date : 2018 Oct
PMID : 30486522
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The mechanism is mainly by inhibiting the activation of nuclear factor (NF-kappaB), mitogen-activated protein kinase (MAPKs) and signal transducers and activators of transcription (STAT) signaling pathways and down-regulating the inflammatory gene expression including tumor necrosis factor-alpha (TNF-alpha), prostaglandin E2 (PGE2), nitric oxide (NO), interleukin-1(IL-1), IL-6, IL-8 and other inflammatory factors. | Dinoprostone | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 2 | The mechanism is mainly by inhibiting the activation of nuclear factor (NF-kappaB), mitogen-activated protein kinase (MAPKs) and signal transducers and activators of transcription (STAT) signaling pathways and down-regulating the inflammatory gene expression including tumor necrosis factor-alpha (TNF-alpha), prostaglandin E2 (PGE2), nitric oxide (NO), interleukin-1(IL-1), IL-6, IL-8 and other inflammatory factors. | Dinoprostone | C-X-C motif chemokine ligand 8 | Homo sapiens |