Title : Prostaglandin E2 promotes Pam3CSK4-induced inflammation in endometrial epithelial cells of cattle.

Pub. Date : 2019 Jan

PMID : 30482421






1 Functional Relationships(s)
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1 The bEECs pre-treated with exogenous PGE2 prior to Pam3CSK4 treatment had an augmented Pam3CSK4-stimulated phosphorylation of protein kinase A (PKA), extracellular signal-regulated kinase (ERK), and IkappaB-alpha; stimulation of TLR2, cyclooxygenase-2, and interleukin-6 functions; and suppression of the activation of PGE2 receptor 4. Dinoprostone NFKB inhibitor alpha Bos taurus