Pub. Date : 2018 Oct-Dec
PMID : 30479586
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The result showed that with increase of TCDD (0.5 nM-10 nM), the expression of TGF-beta3 increased, but after 10 nM TCDD, the expression of TGF-beta3 reduced. | Polychlorinated Dibenzodioxins | transforming growth factor, beta 3 | Mus musculus |
| 2 | The result showed that with increase of TCDD (0.5 nM-10 nM), the expression of TGF-beta3 increased, but after 10 nM TCDD, the expression of TGF-beta3 reduced. | Polychlorinated Dibenzodioxins | transforming growth factor, beta 3 | Mus musculus |
| 3 | The result showed that with increase of TCDD (0.5 nM-10 nM), the expression of TGF-beta3 increased, but after 10 nM TCDD, the expression of TGF-beta3 reduced. | Polychlorinated Dibenzodioxins | transforming growth factor, beta 3 | Mus musculus |
| 4 | In addition, we found that the expression of phosphorylated Smad2/3 and Smad7 was increased by 10 nM TCDD, 10 ng/mL TGF-beta3, or combination of 10 nM TCDD and 10 ng/mL TGF-beta3 induced, but the expression of Smad4 was decreased. | Polychlorinated Dibenzodioxins | transforming growth factor, beta 3 | Mus musculus |
| 5 | In addition, we found that the expression of phosphorylated Smad2/3 and Smad7 was increased by 10 nM TCDD, 10 ng/mL TGF-beta3, or combination of 10 nM TCDD and 10 ng/mL TGF-beta3 induced, but the expression of Smad4 was decreased. | Polychlorinated Dibenzodioxins | transforming growth factor, beta 3 | Mus musculus |
| 6 | These data revealed that the TGF-beta/Smad signaling pathway affected TCDD and TGF-beta3 in MEPM cells. | Polychlorinated Dibenzodioxins | transforming growth factor, beta 3 | Mus musculus |