Pub. Date : 2019 Feb
PMID : 30472069
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We determined that tacrolimus profoundly suppressed CD4 and CD8 T cell proliferation and significantly suppressed Th1 and Th17 responses, as demonstrated by a reduced frequency of IFN-gamma, IL-2, and IL-17 producing CD4 T cells and reduced frequencies of IFN-gamma and IL-2 producing CD8 T cells. | Tacrolimus | interleukin 17A | Homo sapiens |
| 2 | Tacrolimus also inhibits pathogenic Th17 cells coproducing IL-17 and IFN-gamma. | Tacrolimus | interleukin 17A | Homo sapiens |